Well I have been playing RS3 for a couple of days now. I did play it during beta, but, didn't stress test it much. There are a few areas it needs work on.
1. Bank interface. Unless you have mouse over you have to right click the item to see what it is.
2. Mouse over anything does not work unless you turn mouse over on. This is different from RS2 and it covers up part of what the mouse is on.
There a learning curve so part of this may be me unlearning old school stuff and set up the interface properly.